Chemical constituents from root bark of Lycium chinense / 中草药

ABSTRACT

Objective: To investigate the chemical constituents from the root bark of Lycium chinense. Methods The compounds were isolated and purified by various column chromatographies, and their structures were identified by physiochemical properties and spectroscopic data. Results Eighteen compounds were isolated from the EtOH extract of the root bark of L. chinense, which were identified as cannabisin G (1), melongenamide A (2), 7-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-N2,N3-bis(4-hydroxyphenethyl)- 6-methoxy-1,2-dihydronaphthalene-2,3-dicarboxamide (3), 2-methylol-5-hydroxy-pyridine (4), 4-hydroxy-3,5-dimethoxy-phenol (5), ethyl chlorogenate (6), dodecyl ferulate (7), phthalic acid-bis-(2,5-dimethylhexyl) ester (8), dihydrophaseic acid 3′-O-β-D- glucopyranoside (9), phenethyl alcohol xylopyranosyl-(1→6)-glucopyranoside (10), 2-phenylethyl-α-L-arabinopyranosyl-(1→6)-β-D- glucopyranoside (11), tachioside (12), glucosyringic acid (13), isoscoploletin-β-D-glucoside (14), scoploletin (15), digupigan A (16), (+)-lyoniresinol-3α-O-β-D-glucopyranoside (17), and (−)-lyoniresinol-3α-O-β-D-glucopyranoside (18). Conclusion Compounds 1—5 and 7—13 are isolated from this genus for the first time. Compounds 1—14 are isolated from this plant for the first time.