A new sesquiterpenoid from Artemisia lavandulaefolia / 中草药

ABSTRACT

Objective To study the chemical constituents from the aerial parts of Artemisia lavandulaefolia. Methods The constituents were isolated and purified by various column chromatographic techniques, and their structures were identified by spectroscopic analysis. Results Eleven compounds were isolated from 95% ethanol aqueous extract of A. lavandulaefolia and the structures were identified as (4R,5R,7R,10R)-4-hydroxy-eudesma-2,11-dien-1-one (1), 5-epi-eudesma-4(15)-ene-1β,6β-diol (2), eudesma-4(15)-ene-1β,6α-diol (3), methyl 3-oxo-eudesma-1,4,11(13)-trien-12-oate (4), 11β,13-dihydrosantamarin (5), anthemidin (6), scopoletin (7), paeonol (8), ethyl caffeate (9), espeletone (10), and (1R*,2S*,3S*,4S*)-mentha-1,2,3,4-tetrol (11). Conclusion Compound 1 is a new compound named artemilavanone A, and compounds 2-11 are isolated from this plant for the first time.