Analysis of chemical constituents of Jiashen Tablet extract by UPLC-Q-TOF-MS / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 293-304, 2018.
Artículo
en Chino
| WPRIM
| ID: wpr-852239
ABSTRACT
Objective To establish a method for the major content identification of Jiashen Tablet extract by using UPLC-Q-TOF-MS. Methods The chromatographic separation was executed on a Waters ACQUITY UPLC BEH C18 column (2.1 mm × 100 mm, 1.7 μm) with methanol-0.1% formic acid in water by gradient elution. Electrospray ionization (ESI) source was applied and operated in both positive and negative ion mode. Results A total of 72 compounds were found and 68 compounds among them were identified by the methods of comparing reference substance, matching Database and referencing related literature, including 13 phenolic acids, 6 tanshinones, 11 flavonoids and their glycosides, 4 cardiac glycosides, 15 triterpenoid saponins, 7 C21 steroids, and 13 other components. Conclusion This study introduces a comprehensive analysis method of chemical constituents in Jiashen Table extract. The results afford a significant guidance for the study of active constituents and quality control research for Jiashen Tablet.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Traditional and Herbal Drugs
Año:
2018
Tipo del documento:
Artículo
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