Analysis on compatibility and application of Glycyrrhizae Radix et Rhizoma and its herb pairs based on data mining method / 中草药

ABSTRACT

To study the compatibility and application rules of Glycyrrhizae Radix et Rhizoma (GRR) in prescription by data mining. Using computer programming method to transform the information of 26 185 formulas containing GRR in traditional Chinese medicine recipe database to facilitate data analysis. Firstly, the herbs frequently compatible with GRR are found. Then the proportion of GRR and another medicine, family and genus of the diseases treated are counted, the efficacy of formulas as well as their relationship. Through data mining, it is found that GRR often used with Panax ginseng, Angelica sinensis, Poria cocos, Paeonia lactiflora, Zingiber officinale, Atractylodes macrocephala, and other drugs. The most commonly used ratio is 11. These herb-pairs are usually used for internal medical diseases and exerting clearing heat, relieving pain, resolving phlegm and relieving cough and asthma, interior-warming, reinforcing deficiency, and checking retching effect, etc. The properties and functions of GRR are the basis of its compatibility. The compatibility of GMM can increase efficiency and reduce toxicity. This paper will provide a basis for the research of the efficacy of GMM and provide reference for its clinical application.