Chemical constituents of Artemisia sieversiana / 中草药

ABSTRACT

Objective To study the chemical constituents of Artemisia sieversiana. Methods The chemical constituents were separated and purified by column chromatography and HPLC. Their structures were determined on the basis of spectroscopic analyses. Results Seventeen compounds were isolated from A. sieversiana and the structures were identified as yangambin (1), (3R,6R, 7E)-3-hydroxy-4,7-megastigmadien-9-one (2), absinthin (3), anabsin (4), anabsinthin (5), badounoid B (6), gnapholide (7), artabsinolide B (8), 11,10’,11’-epiabsinthin (9), l-borneol-β-D-glucopyranoside (10), 10’,11’-epiabsinthin (11), 2-methyl-2,3,4- trihydroxybutanoic acid-1,4-lactone (12), 3(Z)-hexenyl-β-glucopyranoside (13), pinitol (14), epiloliolide (15), desacetylmatricarin (16), and artabsinolide A (17), respectively. Conclusion Compounds 2, 4-8, 10, and 12-17 are isolated from this plant for the first time.