Research progress on treatment of diabetes with Tibetan medicine Huidouba / 中草药

ABSTRACT

Diabetes is a metabolic disorder characterized by insulin resistance and progressive failure of β cell. It becomes a major disease and causes much attention because of high incidence, high disability, and high morbidity. Traditional Chinese medicine and ethical minority medicine have certain effects on diabetes, such as regulating lipid and losing weight, improving insulin resistance, and reducing hypoglycemia risk, and also have obvious advantage in therapy for vascular complication. Studies show that Tibetan Huidouba can improve metabolism of blood glucose, triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), activity of superoxide dismutase (SOD) and malondialdehyde (MDA) content in diabetic animal. The metabolism includes inhibiting α-glycosidase enzyme, activating peroxisome proliferators activated receptors (PPAR), and inhibiting nicotinamide adenine dinucleotide phosphate coenzyme II (NADPH) oxidase.