Exploration and thinking about lipidomics study strategy based on HILIC-MS technology / 中草药

ABSTRACT

Lipidomics is a new branch discipline of metabolism. The hydrophilic interaction chromatography-mass spectrometry (HILIC-MS) technology is the new study method of lipidomics. The application, operation points, special advantages, and development potential for HILIC-MS were clarified from the angles of biological sample processing method, chromatography, mass spectrometry conditions establishment, and full analysis on quality control. The feasibility of using HILIC-MS technology to solve some lipid metabolism diseases problem in clinical and scientific research of TCM has been investigated.