Chemical constituents from roots of Rumex nepalensis / 中草药

ABSTRACT

Objective: To investigate the chemical constituents from the ethyl acetate extracts in the roots of Rumex nepalensis. Methods: The compounds were isolated by using various chromatographic techniques, such as silica gel column, Sephadex LH-20 column, and semi-preparative HPLC. The structures of these compounds were determined by spectral data analyses. Results: Sixteen compounds were obtained and identified as ferulic acid (1), 7-hydroxy-5-methoxyphthalide (2), methyl 2-acetyl-3,5-dihydroxyphenylacetate (3), methylorsellinate (4), methyl p-hydroxycinnamate (5), 1-(2-Hydroxy-5-Methyl-phenyl)-ethanon (6), methyl syringate (7), 1-(2,4-dihydroxy-6-methylphenyl)-ethanon (8), 4-hydroxy-benzeneethanol (9), isovanillin (10), fallacinol (11), 7-hydroxy-2-methyl-5-methylchromone (12), 3-acetyl-2-methyl-1,5-dihydroxy-2,3-epoxynaphthoquinol (13), emodin (14), chrysophanol (15), and physcion (16). Conclusion: Compounds 12 and 13 are isolated from this plant for the first time, and compounds 1-11 are firstly isolated from the plants of Rumex L..