Poikiloderma Vasculare Atrophicans Showing Features of Ashy Dermatosis in the Beginning
Annals of Dermatology
;
: 197-200, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-8537
ABSTRACT
Poikiloderma vasculare atrophicans (PVA) is a rare poikilodermatous variant of early-stage mycosis fungoides characterized by generalized poikiloderma, atrophy, mottled dyspigmentation, and telangiectasia. In 2001, a 14-year-old male presented with asymptomatic brownish-gray polymorphic macules throughout the body with flexural accentuation. A skin biopsy showed increased melanophages with focal hydropic changes. Ashy dermatosis was considered a possible diagnosis. In 2005, the lesions began to show darkening and lichenification in the lower part of the trunk. In 2011, his skin showed definite poikilodermatous changes, and a biopsy showed band-like inflammatory infiltrations of atypical lymphocytes, epidermal atrophy, and epidermotropism of predominantly CD4-CD8+ atypical T cells. In addition, results of T-cell receptor gene rearrangement analysis were positive. Based on the aforementioned findings, he was diagnosed with PVA. If a patient shows long-standing and progressive hyperpigmentary skin changes, periodic follow-up and repeated skin biopsies are recommended to determine the underlying condition.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Atrofia
/
Piel
/
Enfermedades de la Piel
/
Telangiectasia
/
Biopsia
/
Linfocitos
/
Linfocitos T
/
Estudios de Seguimiento
/
Micosis Fungoide
/
Relación CD4-CD8
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
Límite:
Adolescente
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Annals of Dermatology
Año:
2015
Tipo del documento:
Artículo
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