Chemical constituents of Clematoclethra scandens subsp. actinidioides / 中草药

ABSTRACT

Objective: To further study the chemical constituents of Clematoclethra scandens subsp. actinidioides. Methods: The compounds were isolated and purified by chromatographic methods such as silica gel column chromatography and preparative HPLC, and their structures were identified on the basis of physicochemical properties and spectral data. Results: Nineteen compounds were isolated and identified as vulgarsaponin A (1), 9-hydroxy-megastigma-4,7-dien-3-one-9-O-β-D-glucopyranoside (2), kaempferol-3-O- α-L-rhamnpyranoside (3), quercetin-3-O-α-L-rhamnopyranoside (4), quercetin-3-O-β-D-glucopyranoside (5), hyperoside (6), 1,3,6-tri-O-galloyl-β-D-glucopyranoside (7), 1,2,3,6-tetra-O-galloyl-β-D-glucopyranoside (8), catechin (9), gallocatechin (10), procyanidin B3 (11), protocatechuic acid (12), syringic acid (13), vanillic acid (14), 7-oxokaurenolide (15), stigmast-3,6-dione (16), stigmast-4-en-3,6-dione (17), taraxerol (18), and β-sitosterol (19). Conclusion: Compounds 1-12, and 16 are isolated from the plant of Clematoclethra Maxim. for the first time.