Advances in study on compatibility of licorice and its mechanism of detoxification based on pharmacokinetics / 中草药

ABSTRACT

Licorice is one of Chinese materia medica (CMM) widely used in Chinese medicinal formulae as assistant and guiding medicines, it plays a role in restricting the main drug's toxicity and moderating the property of herbs. Licorice is regarded as a herb that can moderate the property of each herb and remove the hundreds of toxicants. Based on the above characteristics, toxic CMM is always used with licorice. However, the mechanism of the compatibility of licorice is not very clear. It is a good way for us to understand the principle and law of the compatibility of licorice, and to know the relationship between the process and compatibility detoxifying mechanism of licorice through studying on how the licorice has an effect on intracorporal process of the main components in the toxic CMM. The paper mainly summarizes the study on the pharmacokinetics of toxic CMM by compatibility of licorice and its mechanism of pharmacokinetic detoxification.