Isoflavones from Crotalaria sessiliflora / 中草药

ABSTRACT

Objective: To investigate the isoflavones constituents from the whole plant of Crotalaria sessiliflora. Methods: The compounds were isolated by column chromatography and their structures were identified by the spectral data. Results: Twenty-one isflavones were isolated from 75% ethanol extract in the whole plant of C. sessiliflora and identified as 6,7,2'-trimethoxy-4'-hydroxyl isoflavone (1), 7,4'-dihydroxy-5-methoxy isoflavone (2), daidzein (3), 2'-hydroxyl genistein (4), genistein (5), 3'-hydroxyl daidzein (6), genistein 7-O-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranoside (7), genistein 7-O-glucoside (8), glabrone (9), alpinumisoflavone (10), barbacarpan (11), 3'-hydroxyl genistein (12), 4',7-dimethoxy-5-hydroxyl isoflavone (13), pratensein (14), 8-O-methylreyusi (15), eurycarpin A (16), prunetin (17), formononetin (18), 2'-methylalpinumisoflavone (19), hydroxyalpinumisoflavone (20), and desmoxyphllin A (21). Conclusion: Compound 1 is a new compound named sessiliflorin A, compounds 2-3, and 6-21 are isolated from the plant for the first time.