Research progress in regulation of chlorogenic acid on glucose and lipid metabolism / 中草药

ABSTRACT

Chlorogenic acid (CGA) is one of the most abundant phenolic compounds in the human diet and occurs ubiquitously in plant. According to recent research results, CGA exhibits a variety of pharmacologic activities and is closely related to human health. In particular, the biological activities of regulating the metabolism of glucose and lipid and enhancing the sensitivity of insulin of CGA have attracted more and more attention, and gradually become a research hotspot. This article reviewed the research progress in the mechanism of CGA in modulating the effects on glucose and lipids metabolism. Furthermore, the future research direction for CGA is also prospected and presented in order to provide new ideas and approaches for the prevention from obesity, diabetes, and other chronic diseases.