Chemical constituents from Lagotis brevituba / 中草药

ABSTRACT

Objective: To study the chemical constituents from Lagotis brevituba. Methods: The chemical constituents were isolated by solvent extraction, repeated silica gel chromatography, and preparative-HPLC. Their structures were elucidated by physicochemical properties and NMR data. Results: Eleven compounds were isolated from the ethyl acetate and n-butanol fraction of L. brevituba and their structures were identified as arvenin I (1), 3,4-dihydroxyphenylethanol (2), bis (2-ethylhexyl) phthalate (3), plantamajoside (4), mannitol (5), ethyl gallate (6), ethyl 3,4-dihydroxybenzoate (7), dibutyl phthalate (8), β-sitosterol (9), acteoside (10), and mussaenosidic acid (11). Conclusion: Compounds 1-3, 6, and 7 are obtained from the plants in Lagotis Gaertn. for the first time. Compounds 4 and 5 are isolated from L. brevituba for the first time.