Chemical constituents from rhizomes of Paeonia sinjiangensis / 中草药

ABSTRACT

Objective: To investigate the chemical constituents from the rhizomes of Paeonia sinjiangensis. Methods: The chemical constituents were isolated and identified by chromatography on silica gel, Sephadex LH-20, ODS, and RP-HPLC. Their structures were elucidated on the basis of physicochemical properties and spectral analyses. Results: Sixteen compounds were isolated from the 80% ethanol extract from the rhizomes of P. sinjiangensis, and identified as 8-debenzoylpaeoniflorin (1), 4-O-butylpaeoniflorin (2), galloylpaeoniflorin (3), 4-O-methylbenzoylpaeoniflorin (4), benzoylalbiflorin (5), albiflorin R1 (6), 9-O-butylpaeonidanin (7), (Z)-(1S, 5R)-β-pinen-10-yl β-vicianoside (8), gallic acid (9), methyl gallate (10), ethyl gallate (11), isovanillic (12), 6-hydroxycoumarin (13), 3, 4, 23-trihydroxy-24, 30-dinorolean-12, 20 (29)-dien-28-oic acid (14), palbinone (15), and cadina-4, 11-dien-14-oic acid (16). Conclusion: Compound 16 is firstly isolated from the Ranunculaceae family, and compounds 1-15 are isolated from this plant for the first time.