Optimization of wet ultrafine grinding technology for Hirudo extraction / 中草药
Chinese Traditional and Herbal Drugs
;
(24): 2079-2084, 2013.
Artículo
en Chino
| WPRIM
| ID: wpr-855203
ABSTRACT
Objective:
To study the optimal extraction for Hirudo by wet ultrafine grinding technology.Methods:
On the basis of single-factor experiments, the response surface analysis was made for exploring the optimal extraction conditions by wet ultrafine grinding technology for Hirudo, with solid-liquid ratio, soaking time, extraction temperature, and grinding time as independent variable and the anticoagulant activity as the response value. According to Box-Behnken principles, the response surface analysis method with four factors and three levels was used.Results:
The optimum extraction condition for Hirudo by wet ultrafine grinding technology was as follows solid-liquid ratio 112, soaking time 4.9 h, extraction temperature 6.5°C, grinding time 12 min; The anticoagulant activity could reach 20.13 U/g.Conclusion:
The extraction by wet ultrafine grinding technology for Chinese materia medica Hirudo is stable and feasible, and it could be further promoted.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Traditional and Herbal Drugs
Año:
2013
Tipo del documento:
Artículo
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