Chemical constituents in roots and rhizomes of Trillium tschonoskii / 中草药

ABSTRACT

Objective: To investigate the chemical constituents in the roots and rhizomes of Trillium tschonoskii. Methods: The roots and rhizomes of T. tschonoskii were extracted with 70% ethanol and separated by polyamide, silica gel, RP-C18, and Sephadex LH-20 column chromatography. Chemical structures were identified by MS, 1D and 2D NMR spectroscopy. Results: Eight compounds were isolated and their structure were identified as pennogenin-3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (1), pennogenin-3-O-α-L-rhamno-pyranosyl-(1→4)-[α-L- rhamnopyranosyl-(1→2)]-β-D-glucopyranoside (2), pennogenin-3-O- α-L-rhamnopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→4) -[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside (3), pennogenin (4), prosapogenin (5), 7, 11-dimethyl-3-methylene-1, 6-dodecadien-10, 11-dihdroxyl-10-O-β-D-glucopyranosyl-(1→4)-O-β-D-glucopyranoside (6), 7, 11-dimethyl-3-methylene-1, 6-dodecadien-10, 11-dihdroxyl-10-O-β-D- glucopyranoside (7), and astragalin (8). Conclusion: All these compounds are isolated from T. tschonoskii for the first time.