Advances on hyperperfusion-associated cerebral hemorrhage after stenting for middle cerebral artery stenosis / 中国脑血管病杂志

ABSTRACT

Intracranial atherosclerotic stenosis is commonly seen in middle cerebral artery (MCA). Endovascular treatment is one of the therapeutic strategies for MCA stenosis,with postoperative hyperperfusion syndrome (HPS) and hyperperfusion - associated intracranial hemorrhage (HICH) as its serious complications which are associated with poor prognosis. The occurrence of HICH can be understood from the pathophysiology of HPS. Impaired cerebral vascular autoregulation, damaged blood-brain barrier and the effects of nitric oxide and oxygen free radicals may be involved in the occurrence and development of HICH. Combining HPS imaging features is helpful for the diagnosis of HICH. Despite using predictors of HPS to evaluate the risk of HICH has some limitations, it still can help to prevent HICH. In the future, further research is needed to obtain sufficient evidence.