Research progress of hydrogel in tumor immunotherapy / 中国药理学通报

ABSTRACT

Cancer immunotherapy has gained increasing atten-tionin recent years, with combination therapy producing good clinical therapeutic effects. However, the response rate of patients to immunotherapy is still not high, which requires attention to drug utilization and systemic side effects at tumor sites. As a drug-loading platform, hydrogel has great advantages,which can directly deliver anti-tumor drugs to tumor sites, reduce sys temic toxicity, and have good degradability. In this review, the latest advances in drug delivery systems bised on hydrogel plat-forms are summarized, including immunochemotherapy, immu-noradiotherapy and immunophotothermal therapy.