Therapeutic effect of glucomanan on experimental diabetic mice / 中国药理学通报

ABSTRACT

AIM: To observe the therapeutic effect of glucomanan on diabetic mice. METHODS: The diabetic mice induced by alloxan model was established. The mices were randomly divided into the control and treated group to test level of blood glucose respectively. RESULTS: At doses of 100, 200 mg·kg-1 ig 1 and 4 h ahead of time, Glucomanan markedly reduced blood glucose level; At doses of 100, 200 mg·kg-1 ig, it markedly reduced blood glucose level of diabetic mice induced by alloxan; Useing glucomanan 100 mg·kg-1 ig bid x 3 d constantly reduced amount of water-drinking. CONCLUSION: Glucomanan may have significant effect on diabetic mice induced by alloxan.