Research development on the immumodulatory effect of polysaccharide and its mechanism / 中国药理学通报

ABSTRACT

Polysaccharides are important large molecules in the body. It has many functions such as activating the lymphocytes like T, B, NK and Mφ cells, promoting the secretion of cytokines and antibodies through binding to the CR3 receptor of lymphocytes, affecting the concentrations of cellar [Ca2+]i, cAMP, NO and PGE2, and promoting the gene expression of cytokines. Its function also relate to its molecule weight and structure.