The Impact of Clinical Pharmacy Services on the Quality of Warfarin Anticoagulation Therapy Management / 中国药学杂志

ABSTRACT

OBJECTIVE: To evaluate the effects of clinical pharmacy services in patients with warfarin and highlight the important role of clinical pharmacists. METHODS: Patients in need of warfarin were enrolled as intervention group during 2016.9-2017.9 to receive standard anticoagulation management and follow-up provided by clinical pharmacists, and clinical data of patients who meet the inclusion criteria during 2013.7-2015.7 as control group was analyzed retrospectively. International normalized ratio(INR) values, maintenance doses, time to achieve therapeutic range, and etc. were recorded and TTRs (time in therapeutic range) were calculated to compare the outcomes of each group. RESULTS: TTRs in intervention group were significantly higher than those in control group, and so was the percentage of patients with the best quality of warfarin therapy(47.89% vs. 20.09%,P<0.001).Time to achieve therapeutic range was shorter and the frequency of INR test was higher in intervention group compared with those in control group. Patients′ cognitive scores of warfarin therapy were substantially increased after pharmacist′s education. CONCLUSION: Anticoagulation therapy management provided by clinical pharmacists could significantly improve the quality of warfarin therapy.