Clinical Availability of Topographic Auditory Event Related Potentials in Children with Attention Deficit Hyperactivity Disorder / 신경정신의학
Journal of Korean Neuropsychiatric Association
;
: 127-134, 2001.
Artículo
en Coreano
| WPRIM
| ID: wpr-85884
ABSTRACT
OBJECTIVES:
This study was carried out to investigate the clinical availability of topographic auditory event related potential P300 as a biological marker in children with attention deficit hyperactivity disorder(ADHD).METHODS:
The subjects were composed of children with ADHD(n=2216 boys, 6 girl smean age=89.8+/-17.1months) and normal controls(n=2012 boys, 8 girlsmean age=90.6+/-16.8months). Topographic auditory event related potential was measured by "oddball paradigm", and the latencies and amplitudes of P300 of both groups were determined by Global Field Power Measurement. After 8 weeks treatment with methylphenidate, P300 of ADHD children were also measured.RESULTS:
Both P300 latency and amplitude were not different between ADHD children after treatment and normal controls, but significantly different between ADHD children before treatment and normal controls, and between before and after treatment of ADHD children.CONCLUSIONS:
The results implicate that the latency and amplitude of P300 may be considered as state markers of ADHD.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Trastorno por Déficit de Atención con Hiperactividad
/
Biomarcadores
/
Potenciales Evocados
/
Metilfenidato
Límite:
Niño
/
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Journal of Korean Neuropsychiatric Association
Año:
2001
Tipo del documento:
Artículo
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