A new monoterpenoid indole alkaloid from Gardneria multiflora Makino / 中国药学杂志

ABSTRACT

OBJECTIVE: To study the monoterpenoid indole alkaloids in Gardneria multiflora Makino. METHODS: The dried plants of G. multiflora Makino were extracted with 95% ethanol. After removal of solvent, the residue was diluted with water, then extracted with petroleum ether and chloroform to obtain crude alkaloids. Column chromatograghy on silica gel, Rp-18, and Sephadex LH-20 were applied for the isolation and purification of crude alkaloids. The structure was elucidated based on detailed spectroscopic evidence. RESULTS: One monoterpenoid indole alkaloid was isolated from this plant. CONCLUSION: Compound gardmultimine A (1) is a new compound.