Phenolic acid compounds from anemone altaicae rhizoma / 中国药学杂志

ABSTRACT

OBJECTIVE: To study the chemical constituents in the roots of Anemone altaica. METHODS: The isolation and purification of the compounds were performed by chromatography on Diaion HP-20, Sephadex LH-20, and silica gel, combined with preparation liquid chromatography. Their structures were determined by comparison of their physicochemical characteristics and spectral data with literatures. RESULTS: Eleven compounds were obtained, and their structures were identified as methyl feruloyl-tartarate A (I), methyl feruloyl-tartarate B (II), ethyl feruloyl-tartarate B (III), mono-methyl feruloyl-lactate (IV), dimethyl feruloyl-lactate (V), vanillic acid-4-O-β-D-glucopyranoside (VI), p-hydroxybenzoic acid glucoside (VII), methyl chlorogenate (VIII), 3-O-fernloylquini acid (IX), 5-O-feruloyl-3-O-(β-D-glucopyranosyl)-2-deoxy-D-ribono-γ-lactone (X), and carboxymethyl isoferulate (XI). CONCLUSION: Compounds I-V are new compounds, and are speculated to be a man-made products. Compounds VI-XI are isolated from the plants of anemone genus for the first time.