Antimalarial activity of Isodon yuennanensis / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 612-615, 2016.
Artículo
en Chino
| WPRIM
| ID: wpr-859135
ABSTRACT
OBJECTIVE:
To evaluate the antimalarial activity of Isodon yuennanensis for the development of neo-style antimalarial drugs or lead compounds from plants.METHODS:
The crude extract and compounds from I. yuennanensis were screened for antimalarial activities by β-hematin formation inhibition assay, and the results were expressed as IC50 values.RESULTS:
The crude extract, as well as some compounds, showed β-hematin formation inhibition activities in different degrees.CONCLUSION:
The ethyl acetate fraction derived from the 70% acetone extract of I. yuennanensis and the compounds 2, 12, and 13 obtained from the ethyl acetate fraction are worthy of deeper research due to their significant antimalarial activities.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Pharmaceutical Journal
Año:
2016
Tipo del documento:
Artículo
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