Review of the establishing methods of premature ovarian failure's animal model / 中国药学杂志

ABSTRACT

Premature ovarian failure whose pathological and physiological performances are very complex can be caused by a variety of reasons. And its animal models can be established through many ways according to the etiology, such as chemotherapy drug model, immune damage model, galactose metabolism model, gene knockout model and other ways. Different models have different characteristics. In this paper, kinds of animal models of premature ovarian failure and their features were reviewed, what would provide ideas for related basic research.