Application of lipid carriers combining microneedle in transdermal drug delivery / 中国药学杂志

ABSTRACT

As a new type of transdermal drug delivery, microneedles can transiently break the barrier properties of skin and the lipid carriers offer a wide range of benefits including control of skin permeation, protection of the encapsulated drug and decrease of the drug toxicity and skin irritation, lipid carriers combining microneedle will bring new opportunities for developing transdermal drug delivery preparations of traditional Chinese medicine. By researching the relevant literatures at home and abroad, the enhancing mechanisms, administration and influence for percutaneous absorption of lipid carriers combining microneedle were reviewed and the application of lipid carriers combining microneedle in transdermal drug delivery was summarized.