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Review on chemistry and anti-tumor effect of lentinan / 中国药学杂志
Chinese Pharmaceutical Journal ; (24): 1536-1539, 2013.
Artículo en Chino | WPRIM | ID: wpr-860225
ABSTRACT

OBJECTIVE:

To introduce the progress on the study of lentinan chemistry and anti-tumor effect and provide references for research and clinical applications.

METHODS:

Reviewed and analyzed many literatures of lentinan, summarized them compres-sively and introduced the progress on the extraction and purification of lentinan, structural analysis and anti-tumor effect in recent years.

RESULTS:

As the extraction and purification methods for lentinan were different, the polysaccharide compositions and structures were different, and the main forms were homopolysaccharide(glucan) and heteropolysaccharide. And its anti-tumor effects were related to immune enhancement, inhibition of tumor growth effect, synergistic anti-tumor chemotherapy and so on.

CONCLUSION:

Chemical properties of lentinan is closely related with the anti-tumor effect, and further in-depth research on the structure-activity relationships of lentinan is needed to provide better scientific basis for the comprehensive development and application of lentinan.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Pharmaceutical Journal Año: 2013 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Idioma: Chino Revista: Chinese Pharmaceutical Journal Año: 2013 Tipo del documento: Artículo