Study on chemical constituents of Ginkgo biloba kernel / 中国药学杂志

ABSTRACT

OBJECTIVE: To study the chemical constituents of Ginkgo biloba kernel. METHODS: The chemical constituents were isolated by silica gel chromatography, and their structures were elucidated by physical-chemical and spectroscopic data. RESULTS: Nineteen compounds were isolated and their structures were identified as hexacosanoic acid (I), palmitic acid (II), ginnol(III), β-sitosterol (IV), 2, 3-dihydroxypropyl hexadecoate (V), ursolic acid(VI), sciadopitysin (VII), ginkgetin (VIII), isoginkgetin (IX), daucosterol(X), ginkdolide A (XI), ginkdolide B (XII), ginkdolide C (XIII), uracil(XIV), coniferin (XV), liquirtin (XVI), adenosine (VII), D-glucose (XVIII) and sucrose (XIX). CONCLUSION: Compounds VI, XV-XVII are obtained from this plant for the first time, compounds I-V, VII-X and XIV are obtained from Ginkgo biloba kernel for the first time. Copyright 2012 by the Chinese Pharmaceutical Association.