Spectral CT findings of focal organizing pneumonia and peripheral lung cancer / 中国医学影像技术

ABSTRACT

Objective: To observe the energy spectral CT manifestations of focal organizing pneumonia (FOP) and peripheral lung cancer (PLC). Methods: Data of 40 patients with FOP (FOP group) and 60 patients with PLC (PLC group) confirmed by pathology who underwent chest dual-phase energy spectral CT were retrospectively analyzed. CT40~100 keV values on single energy images, iodine concentration, water concentration and effective atomic number at arterial and venous phase of lesions were measured and recorded, respectively. The corresponding energy spectral curve was drawn, and the slope of the curve was calculated. The quantitative parameters were compared between 2 groups. Results: There was no statistically differences of patients' age, gender, clinical symptoms nor lesions' size or location between 2 groups (all P>0.05). CT40 keV, CT50 keV, CT60 keV and CT 70 keV values, λ70 keV, iodine concentration, effective atomic number at arterial phase in PLC group were all higher than those in FOP group (t=3.46, 3.08, 3.08, 2.03, 2.32, 2.69, 2.73, all P0.05). Conclusion: Energy spectral CT findings of FOP and PLC had certain difference, providing references for differential diagnosis of FOP and PLC.