Clinical and imaging characteristics of invasive Klebsiella pneumoniae liver abscess syndrome / 中国医学影像技术

ABSTRACT

Objective: To observe the clinical and imaging characteristics of invasive Klebsiella pneumoniae liver abscess syndrome (IKLAS). Methods: Clinical and imaging findings of 18 patients with IKLAS were retrospectively analyzed. Results: Clinical manifestations included fever (n=18), chills (n=11), some accompanied by respiratory, digestive, nervous system symptoms and visual impairment. Among 18 patients, 13 were found with diabetes. Laboratory examinations showed rise of infection indicators and hepatic function abnormality. Liver abscess located at right lobe in 15 cases, at left lobe in 2 cases, simultaneously involved at both right and left lobe in 1 case, sized 2.45-10.27 cm, mean (5.70±2.35)cm, and gas in abscess was observed in 3 cases. Lung lesions mainly located at the peripheral subpleural areas, CT showed nodules without cavity (18/18, 100%), with cavity (15/18, 83.33%) or honeycomb-like (13/18, 72.22%) abscess, with halo sign (4/18, 22.22%), reverse halo sign (3/18, 16.67%), consolidation shadows (3/18, 16.67%), peripheral wedge shadow (2/18, 11.11%), nourishing blood vessels (2/18, 11.11%), ground glass opacity (1/18, 5.56%) and bilateral pleural effusion (15/18, 83.33%). Two patients were found with intracranial and eye infection. Conclusion: IKLAS has certain characteristic imaging manifestations, which are helpful to diagnosis combining with clinical characteristics.