CT manifestations and clinical features of ovarian granulosa cell tumor in children / 中国医学影像技术

ABSTRACT

Objective: To analyze CT manifestations and clinical features of pediatric ovarian granulosa cell tumor (GCT)in children. Methods: Preoperative CT images and clinical data of 12 girls with ovarian GCT were retrospectively analyzed. CT manifestations of ovarian GCT, including the quality and size of tumor, calcification, enhancement degree, vessels in tumor, size of uterine, pelvic effusion and lymphadenovarix were observed. Results: The chief complaints included abdominal pain, precocious puberty or virilization. Preoperative serum estradiol level increased in 9 patients and serum testosterone level increased in 2 patients. Solid tumor (n=2), cystic-solid (n=8) and cystic mass (n=2) were showed in plain CT images, with the median diameter of 82.50 (46.75, 111.00)mm. Calcifications (n=1) and massive pelvic effusion (n=2) were rare, whereas hysterauxesis was common (n=9). After administration of contrast media, the solid components of tumors enhanced obviously, and vessels in tumors were seen in 9 cases. The cystic mass did not obviously enhance. No obvious enlarged lymph node was found in all patients. Conclusion: Ovarian neoplasm with hysterauxesis and rich vascular supply showed on CT highly suggest ovarian granulosa cell tumor in children combined with specific endocrine symptoms and changes in hormone levels and tumor markers.