Quantitative evaluation of morphology and function of left atrial appendage in atrial fibrillation patients with real-time three-dimensional transesophageal echocardiography / 中国介入影像与治疗学

ABSTRACT

Objective: To investigate the feasibility of quantitative assessment of the left atrial appendage (LAA) morphology and function in atrial fibrillation (AF)patients with real-time three-dimensional transesophageal echocardiography (RT-3D-TEE). Methods: Totally 56 patients with paroxysmal AF (paroxysmal group), 26 patients with sustained AF (sustained group) and 11 healthy controls (control group) were enrolled. RT-3D-TEE was used to measure LAA parameters of 3 groups. Results: Compared with control group, LAA end-diastolic volume (LAA-EDV), end systolic volume (LAA-ESV), opening maximum area (Amax) and minimum area (Amin) of paroxysmal group increased, while LAA ejection fraction (LAA-EF), maximum evacuation speed (Vep), area change rate (A%) and diameter change rate (D%) of paroxysmal group decreased (all P0.05). LAA-EF was negatively correlated with ESV (r=-0.73, P0.05). Conclusion:RT-3D-TEE can quantitatively analyze the changes of LAA morphology and function, and has certain clinical significance for evaluating the condition of AF patients.