Progress of pertussis toxin / 国际儿科学杂志

ABSTRACT

Pertussis is an acute respiratory infectious disease caused by Bordetella pertussis.In recent years, pertussis reappearance makes it become one of the important diseases affecting human health.Pertussis toxin is an important virulence factor produced by Bordetella pertussis.It is an important component of acellular pertussis vaccine, and is related to most clinical symptoms and fatal pertussis.This paper reviews the molecular structure and pathogenesis of pertussis toxin.