Progress on the relationship between atmospheric PM2.5 and bronchial asthma / 国际儿科学杂志

ABSTRACT

Bronchial asthma is one of the most common childhood chronic respiratory diseases characterized by airway hyperresponsiveness and reversible airflow limitation.Air pollution, especially PM2.5(fine particle size ≤2.5 microns)has a significant effect on asthma, through oxidative stress, immune inflammatory injury, airway hyperresponsiveness and other mechanisms.This paper describes the source, composition, physical and chemical properties of PM2.5, the mechanism of PM2.5 induced asthma, and its effects on acute bronchial asthma attack, acute outpatient consultation rate, hospitalization rate, lung function and exhaled nitric oxide(FeNO).