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The Effect of Spinal Cord Injury on Pituitary-Testicular Hormone Axis in Rats / 대한비뇨기과학회지
Korean Journal of Urology ; : 947-951, 1998.
Artículo en Coreano | WPRIM | ID: wpr-86302
ABSTRACT

PURPOSE:

To investigate the effect of spinal cord injury(SCI) on male reproductive function, we evaluated changes of pituitary-testicular hormonal level at various time intervals in spinal cord injured rats. MATERIALS AND

METHODS:

SCI was produced in 30 sexually mature Sprague-Dawley rats by T10 spinal cord transection. 20 controls received similar surgery without transection. Testosterone concentrations in the serum and testis, serum levels of follicle-stimulating hormone(FSH) and leutenizing hormone(LH) were measured with radioimmunoassay. Two way analysis of variance(ANOVA) was performed.

RESULTS:

Testosterone levels in the serum and testis were lower at 2 weeks after injury than in controls, but others were not. Serum levels of FSH and LH were similar in both group.

CONCLUSIONS:

Spinal cord injury in rats induced impairment of testosterone production in testis at 2 weeks.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Espermatogénesis / Médula Espinal / Traumatismos de la Médula Espinal / Vértebra Cervical Axis / Testículo / Testosterona / Radioinmunoensayo / Ratas Sprague-Dawley Límite: Animales / Humanos / Masculino Idioma: Coreano Revista: Korean Journal of Urology Año: 1998 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Espermatogénesis / Médula Espinal / Traumatismos de la Médula Espinal / Vértebra Cervical Axis / Testículo / Testosterona / Radioinmunoensayo / Ratas Sprague-Dawley Límite: Animales / Humanos / Masculino Idioma: Coreano Revista: Korean Journal of Urology Año: 1998 Tipo del documento: Artículo