Research progress of white fat browning in regulation of fat metabolism / 国际外科学杂志

ABSTRACT

The adipose tissue in mammalian can be classifieded into white adipose tissue and brown adipose tissue according to color and function. White adipose tissue can change into a new type of adipocyte - -Beige adipocyte under the condition such as sympathetic excitation. The process white adipose tissue is induced to produce beige adipose tissue is called browning of white adipose tissue. The dynamic balance between white adipose tissue and beige adipose tissue is closely related to the homeostasis of metabolism. Studying the signal transduction pathway of the white to brown transformation of adipose tissue can provide a new way to correct obesity and alleviate the disorder of obesity related glucose and lipid metabolism. The role, significance and influencing factors in metabolic regulation of white adipose tissue browning were discussed in this paper.