Mechanism, diagnosis and treatment of coma caused by craniocerebral injury / 国际外科学杂志

ABSTRACT

Coma caused by craniocerebral trauma is one of the difficulties in the diagnosis and treatment of neurosurgery. Its pathogenesis is complex, and there are some uncertainties in diagnosis and treatment. There are still many questions to be further studied in this field. In this paper, we searched and consulted the literature, combined with the latest clinical guidelines, reviewed pathophysiological mechanism, special clinical symptoms, diagnostic criteria, advanced neuroimaging and electrophysiological techniques in the diagnosis and treatment of consciousness disorders, as well as the latest progress and main achievements in treatment strategies. It is suggested that individualized intervention therapy with neuroimaging and electrophysiological evaluation of functional and structural injury may be one of the important research directions in the future.