Application of metagenomics detection of pathogenic microorganisms in neonatal infectious diseases / 中华实用儿科临床杂志

ABSTRACT

The clinical manifestations of neonatal infectious diseases are diverse, lacking specificity, and it may involve multiple organs or systems.At present, there are many clinical indicators of neonatal infectious diseases, each of which has its advantages and disadvantages, and it is difficult to meet the requirements of current diagnosis and treatment.Clinical metagenomic next-generation sequencing (mNGS) can accurately and efficiently analyze the genetic material information of all pathogenic microorganisms, so as to directly detect pathogenic microorganisms for diagnosis and treatment, which has important reference value for the diagnosis of neonatal infectious diseases.Now, the recent advances in metagenomics detection of pathogenic microorganisms and its application in neonatal infectious diseases were reviewed.