Clinical analysis on flexible bronchoscopy intervention therapy in 18 children with primary tracheobronchial tumors / 中华实用儿科临床杂志

ABSTRACT

Objective:To summarize the clinical data of 18 children with primary tracheobronchial tumors, and to investigate the safety and effectiveness of bronchoscopy intervention therapy.Methods:The clinical features, signs, imaging and bronchoscope characteristics, pathology types, endoscopy intervention therapy methods, and outcomes of 18 patients with primary tracheobronchial tumors treated in Qilu Children′s Hospital of Shandong University from January 2013 to August 2019 were retrospectively analyzed.Results:The patients aged from 2 years old to 12 years old, and the ratio of male and female was 1.71∶1.There were 8 cases of mucoepidermoid carcinoma, 7 cases of inflammatory myofibroblastoma, 1 case of infant fibrosarcoma, 1 case of intermediate vascular tumor, and 1 case of acinar cell carcinoma.All 18 patients received the biopsy under general anesthesia to determine the pathological type of tumor and underwent the interventional therapy to relieve airway obstruction.No complications such as massive bleeding, pneumothorax, and mediastinal emphysema were observed during and after operation.The endoscope examination was applied to assess the curative effect 1 week after the surgery, complete response 17 case, inefficiency 1 case, and the overall effective rate was 94%.Conclusions:It is safe and reliable to treat primary tracheobronchial tumor by bronchoscopy intervention therapy, which can be used as a palliative treatment and create conditions for further radical operation.It may even become a radical cure for tracheobronchial tumors.