The relationship between the initial pathological parameters of renal biopsy and the prognosis of Henoch-Schonlein purpura nephritis in the childhood / 中国小儿急救医学

ABSTRACT

Henoch-schonlein purpura is the most common vasculitis in the childhood.The prognosis of Henoch-schonlein purpura is mainly dependent on the renal component of the disease, which is equal to the severity of Henoch-schonlein purpura nephritis(HSPN). To predict the outcome of the HSPN, the pathology of renal biopsy is still remaining the gold standard.The conventional histological classification of the International Study of Kidney Disease in Chlidren(ISKDC), which is facing severe challenges in evaluating the prognosis of the HSPN, is imprecise.So it′s very necessary to recognize the relationship between specific pathological changes and prognosis of HSPN.So we reviewed the relationship between specific pathological changes and the prognosis prediction of HSPN in this paper, hoping to guide the clinical work.