Progress in arsenic-induced programmed cell death / 中华地方病学杂志
Chinese Journal of Endemiology
;
(12): 542-546, 2020.
Artículo
en Chino
| WPRIM
| ID: wpr-866155
ABSTRACT
With the deepening of the research on the "two sides" of arsenic from poison to medicine, arsenic has attracted extensive attention in affecting programmed cell death (PCD) and causing damage to a variety of organs. Recent studies have showed that reactive oxygen species (ROS) produced by intracellular arsenic metabolism is closely related to PCD induction. However, the specific mechanism is still unclear. In this paper, we have reviewed the main PCD forms, such as apoptosis, autophagy and necroptosis induced by arsenic via ROS and their possible mechanisms, in order to provide basic information for further research and prevention of arsenic toxicity, which is helpful for clinical development and utilization of arsenic in the treatment of tumors and related diseases.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Endemiology
Año:
2020
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS