Semantic features and brain functional neuroimaging / 中华行为医学与脑科学杂志

ABSTRACT

Approximately a third of stroke patients have aphasia.As the most common clinical manifestation of aphasia patients, speech communication difficulties will lead to emotional disorders, reduce communication participation and even reduce quality of life. Distinct from dementia patients, aphasia patients after stroke are still able to discriminate and recognize the acquired semantic knowledge but cannot extract randomly and name correctly compared with healthy people. It has been proved that semantic treatment can maintain a longer duration of efficacy than phonological treatment in speech therapy. Semantic feature analysis therapy has been widely used in clinical practice and achieved good behavioral therapeutic effects. However it remains unknown whether the impaired brain function will be restored. To explore the semantic processing of human brain, it is necessary to identify " what" category of semantic features have been activated, " where" the activation center and related activities can be seen, " when" generates activities and affect " how" processing by describing the time sequence. In order to explore the neuroimaging therapeutic effects of training materials with specific semantic features, the paper reviews the influence of semantic features in spatial, temporal and frequency relationships on the brain functional activity, and prospect the future research and clinical application.