Neuroimaging in the diagnosis and differentiation of Alzheimer′s disease / 中华神经科杂志

ABSTRACT

Neuroimaging is of great value in the diagnosis and differentiation of Alzheimer′s disease. Structural imaging, especially structural magnetic resonance, can show the characteristic changes of brain atrophy in patients with Alzheimer′s disease, and effectively identify lesions in the brain. Functional imaging, mainly the molecular imaging of positron emission tomography can achieve intracranial retention of tracer that binds to the β-amyloid, which is of great value for the pathophysiological diagnosis of Alzheimer′s disease. This article introduces the application value of structural and functional magnetic resonance imaging, positron emission tomography, single-photon emission computed tomography and other imaging examinations in the diagnosis and differentiation of Alzheimer′s disease.