Advances in Research on Constituents and Pharmacological Effects ofArtemisia argyi Essential Oil / 中国实验方剂学杂志

ABSTRACT

Artemisia argyi is a perennial aromatic herb，which has used as a medicine for its leaves.It is spicy，bitter and warm，it has a small poison，it acts on the liver，spleen and kidney.According to traditional Chinese medicine（TCM），it has the functions of warming the bleeding，relieving cold and pain，dispelling dampness and itching，and so on.Previous researches have shown that A. argyi is used for treatment of various diseases，including pneumonia，gastritis，and hepatitis.Modern pharmacological studies have shown that it has a variety of antibacterial，antioxidant，insect-resistant，anti-inflammatory，immunomodulative and other activities，which depend on their complex chemical constituents，mainly including essential oil，flavonoids，tannins and polysaccharides.The A. argyi essential oil（AAEO）are the main active parts isolated from the extract of A. argyi，including ethers，alcohols，monoterpenes，sesquiterpenes，and other compounds，which have broad-spectrum antibacterial，antioxidant，anti-inflammatory，anti-tumor，analgesia，asthma relief and immune regulation，and have broad-spectrum biological activities.By studying the literatures at home and abroad in recent years，the chemical composition of AAEO was sorted out，and the chemical composition characteristics and contents of it prepared by different extraction methods were summarized，as well as the common chemical components detected in AAEO at the present stage.The author also reviewed a variety of pharmacological activities of AAEO，focusing on its anti-inflammatory，anti-tumor，antibacterial，antioxidant and other activities，and found that it has a good drug development prospect for inflammation，tumor，bacterial diseases and so on.In order to better exploit and utilize AAEO natural resources，the author analyzes the existing problems in the research and development process of it and puts forward that it is necessary to further and systematically explore its chemical components，pharmacological effects，basis of medicinal substances and mechanism of action，so as to lay a foundation for the comprehensive development and utilization of AAEO.