Correlation of diopters and ocular biometric parameters in youth with myopia / 国际眼科杂志(Guoji Yanke Zazhi)

ABSTRACT

@#AIM: To investigate the correlation of myopia severity(SE)with axial length(AL), intraocular pressure(IOP), central corneal thickness(CCT), anterior chamber depth(ACD), and mean keratometry(Km)in young myopia patients.<p>METHODS: In the retrospective study, we selected myopic patients who were diagnosed in Lanzhou Huaxia Eye Hospital from Mar. 2017 to Jul. 2019. They were divided into four myopia groups, A(mild), B(moderate), C(high), and D(hyper)based on the SE. We then measured and analyzed the correlation of the degree of myopia with AL, IOP, CCT, ACD, and Km. Differences between groups were analyzed by one-way analysis of variance. Relationships between the relevant factors were analyzed by Pearson correlation analysis.<p>RESULTS: The SE were(-2.38±0.49)D,(-4.60±0.82)D,(-7.40±1.08)D and(-11.58±1.23)D in the mild, moderate, high and hyper myopia groups respectively. The AL were(24.55±0.72)mm,(25.68±0.77)mm,(26.75±0.64)mm and(28.00±0.56)mm in the respective myopia groups. The IOP were(14.68±3.18)mmHg,(14.78±2.81)mmHg,(15.19±2.66)mmHg,(15.70±2.68)mmHg in the respective myopia groups. The ACD were(3.41±0.24)mm,(3.34±0.25)mm,(3.32±0.25)mm and(3.24±0.27)mm in the respective myopia groups. The Km were(42.96±1.22)D,(43.02±1.43)D,(43.29±1.47)D and(43.56±1.47)D in the respective myopia groups. There were no significant differences for CCT among the different groups. SE was significantly positive correlated to AL(<i>r</i>=0.851, <i>P</i><0.001), IOP(<i>r</i>=0.104, <i>P</i><0.001), CCT(<i>r</i>=0.066, <i>P</i><0.001)and Km(<i>r</i>=0.157, <i>P</i><0.001); SE was negative correlated to ACD(<i>r</i>=-0.129, <i>P</i><0.001).<p>CONCLUSION: In our study, there is a positive correlation between the progression of myopia and the increase in AL, IOP, CCT, and Km. There is a negative correlation between myopia and ACD.