Progress of researches on the involvement of indoleamine 2, 3-dioxygenase in regulation of parasite-host immune interactions / 中国血吸虫病防治杂志
Chinese Journal of Schistosomiasis Control
;
(6): 209-212, 2020.
Artículo
en Chino
| WPRIM
| ID: wpr-876716
ABSTRACT
Indoleamine 2, 3-dioxygenase (IDO) is an important immunoregulatory enzyme, which mediates immune effects by depleting tryptophan and producing multiple metabolites. Recently, the studies on the immune function of IDO have been mostly restricted in tumors and autoimmune diseases. Nevertheless, there are few studies pertaining to the role of IDO in parasitic diseases, notably in parasite-host immune interactions. This review mainly describes IDO-mediated immunoregulatory effects and its regulation of parasite-host interactions, so as to provide insights into the development of immune intervention schemes against parasitic diseases.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Schistosomiasis Control
Año:
2020
Tipo del documento:
Artículo
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