Correlation of Progression Rate between Optic Disc Cupping and Visual Field Damage in Treated Primary Open Angle Glaucoma

ABSTRACT

PURPOSE: To know the rate of optic disc cupping and visual field progression with correlation among them, and identify clinical factors associated with them. METHODS: Forty patients with POAG who treated over 10 years were evaluated, Cup progression rate was evaluated by using computer-aided planimetry and visual field declination was evaluated with Goldmann perimetry and manual grid template system. Optic disc cupping and visual field progression correlations were estimated using linear regression and all related clinical factors were evaluated using a multiple regression model. RESULTS: Optic disc cupping progression started from inferotemporal to superonasal, to superotemporal and to inferonasal portion (total 0.0067/year) and visual field loss progressed superonasal, inferonasal, superotemporal, inferotemporally (total -1.07%/year) in order with significant correlation. Incisional surgery before visit and higher yearly average higher intraocular pressure showed faster optic disc cup progression and higher initial intraocular pressure and lesser antiglaucoma medications at initial visits showed faster visual field progression. CONCLUSIONS: In treated patients with POAG, the rate of disc cupping and visual field decline showed slow progression rate with significant correlation and various clinical factors affected.