Effect of / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 356-363, 2021.
Artículo
en Inglés
| WPRIM
| ID: wpr-878371
ABSTRACT
Objective@#This study aimed to investigate the effects of @*Methods@#In this study, 0.1% DMG was supplemented in 20% casein diets that were either folate-sufficient (20C) or folate-deficient (20CFD). Blood and liver of rats were subjected to assays of Hcy and its metabolites. Hcy and its related metabolite concentrations were determined using a liquid chromatographic system.@*Results@#Folate deprivation significantly increased pHcy concentration in rats fed 20C diet (from 14.19 ± 0.39 μmol/L to 28.49 ± 0.50 μmol/L; @*Conclusion@#DMG supplementation exhibited hypohomocysteinemic effects under folate-sufficient conditions. By contrast, the combination of folate deficiency and DMG supplementation has deleterious effect on pHcy concentration.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Sarcosina
/
Biomarcadores
/
Distribución Aleatoria
/
Cromatografía Liquida
/
Ratas Wistar
/
Suplementos Dietéticos
/
Dieta
/
Deficiencia de Ácido Fólico
/
Homocisteína
/
Hígado
Límite:
Animales
Idioma:
Inglés
Revista:
Biomedical and Environmental Sciences
Año:
2021
Tipo del documento:
Artículo
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